Introduction Laparoscopic cholecystectomy is the gold standard for treatment of acute cholecystitis. However in patients with high surgical risk, comorbidities, or advanced age, cholecystectomy is associated with high rates of morbidity and postoperative mortality. Percutaneous cholecystostomy (PC) is a minimally invasive procedure that can be an alternative in high risk and critically ill patients. This can act as a bridging procedure followed by an interval cholecystectomy (IC) or a definitive procedure in patients who are unlikely fit for surgery. The purpose of this study is do determine optimal timing of cholecystectomy after PC. Method A retrospective study of patients that underwent percutaneous cholecystostomy followed by interval cholecystectomy from 2017 to 2022 at a tertiary centre in Perth was analysed. Patients were divided into 2 groups based on timing of interval cholecystectomy. Outcome included basic demographic, intraoperative and perioperative outcomes. Result 26 patients were included in this study and were divided into 2 groups: interval cholecystectomy <10 weeks (n=6) and >10weeks (n=20). Of those identified, 69% were male with a mean age of 64.5. The median time of PC to IC was 111.5 days. There was no statistically significance variation in demographic, intraoperative and perioperative outcomes between patients undergoing IC within or after 10 weeks of PC. Further larger studies are needed to confirm the outcome and determine optimal timing of IC