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Contemporary outcomes of congenital diaphragmatic hernia
Verbal Presentation

Verbal Presentation

4:30 pm

01 May 2026

Meeting Room M3

RESEARCH PAPERS

Talk Description

Institution: Sydney Children's Hospital, Randwick - NSW, Australia

Purpose: To review contemporary outcomes of congenital diaphragmatic hernia within the Australian setting. Methodology: A retrospective review was performed of all patients with congenital diaphragmatic hernia managed at the Sydney Children’s Hospital from January 2000 – December 2024 (inclusive). Patients who presented outside of the neonatal period were excluded. The medical records of each patient were reviewed with the primary outcome being mortality, and secondary outcomes including use of ECMO and length of stay. Each five year period was analysed separately (P1 2000-2004, P2 2005-2009, P3 2010-2014, P4 2015-2019, P5 2020-2024). Ethics approval was obtained from the local research governance body. Results: 159 patients with CDH were born during the study period (left-sided n= 133, right-sided n= 26). Rates of prenatal diagnosis increased over time (50-61% during P1-3, compared with 72-79% P4-5), with similar increase in numbers of inborn compared with outborn patients. Mortality remained stable over the study period, ranging from 20-24% between time periods. Median length of stay did however decrease over time (P1 = 21 days, P2 = 26, P3 = 15, P4 = 14, P5 = 13). 136/159 (86%) underwent surgical repair at a median age of 3 days, with a trend towards increasing use of thoracoscopy. ECMO was utilised in 7 cases (4.4%). Four patients were commenced on ECMO pre-operatively, two post-operatively, and one did not have attempt at repair. Mortality in patients who required ECMO was 57% (4/7). Conclusion: We report favourable outcomes of CDH in terms of survival compared with published data worldwide, despite low use of ECMO. Although overall survival remained stable across the 25-year period of this study, we observed an increased rate of prenatal diagnosis, as well as a decrease in length of stay for surviving patients.
Speakers
Contributors
Authors

Dr Kiera Roberts - , Ms Janelle Young - , Dr Hari Ravindranathan - , Prof Susan Adams -

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